Mapping of Genetic Markers

Molecular mapping helps in identifying the location of specific markers inside the genome. There are two kinds of maps. To start with is a physical map, which identifies the chromosome and area on it. Furthermore, there is a linkage map recognizes how specific genes are connected to different genes on a chromosome. In some organisms, maps appeared to be "full" of loci of known phenotypic impact and estimations demonstrated that the chromosomal intervals between genes needed to contain DNA. These gaps couldn't be mapped by linkage analysis, on the grounds that there were no markers in those regions. A molecular marker is a site of heterozygosity for some sort of DNA variety. Such a "DNA locus," when heterozygous, can be utilized as a part of mapping analysis. 

 

  • Mapping depends on the recombination frequency between molecular markers
  • Use of restriction fragment length polymorphisms in mapping
  • Use of polymorphism of VNTRs in mapping

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